MODERN ISSUES OF MEDICINAL RESISTANCE (LITERATURE REVIEW)
Keywords:
According to theAbstract
Classification and epidemiological significance of drug resistance
Drug resistance is the loss of the ability of microorganisms to be exposed to the
standard or usual therapeutic concentration of a drug used for treatment [1]. This
situation sharply reduces the effectiveness of treating infectious diseases, aggravates
the course of the disease, increases mortality rates, and places a significant economic
burden on the healthcare system [2].
References
1. Munita JM, Arias CA. Mechanisms of antibiotic resistance. Microbial
Spectrum. 2016;4 (2). doi:10.1128/microbiolspec.VMBF-0016-2015.
2. Antimicrobial Resistance Collaborators. Global burden of bacterial
antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399 (10325):629
655. doi:10.1016/S0140-6736 (21) 02724-0
3. World Health Organization. WHO bacterial priority pathogens list, 2024: A
global priority list of antibiotic-resistant bacteria to guide research, discovery, and
development of new antibiotics. Geneva: WHO; 2024.
4. Munita JM, Arias CA. Multidrug-resistant, extensively drug-resistant and
pandrug-resistant bacteria: An international expert proposal for interim standard
definitions for acquired resistance. In: Updates on Antimicrobial Resistance. 2016:1
22. (See also Munita JM, Arias CA. Mechanisms of drug resistance. In: Gram-Positive
Pathogens. 3rd ed. ASM Press; 2019).
5. Cosentino F, Viale P, Giannella M. MDR/XDR/PDR or DTR? Which definition
best fits the resistance profile of Pseudomonas aeruginosa? Curr Open Infect Dis.
2023;36 (6):564-571. doi:10.1097/QCO.0000000000000980.
