CANCER DISEASES AND EARLY DIAGNOSIS: A MODERN PERSPECTIVE ON THE PROBLEM
Keywords:
Keywords: oncology, malignant neoplasms, early diagnosis, screening, carcinogenesis, tumor markers, prevention.Abstract
Abstract: Oncological diseases represent one of the most acute medical and social problems of modern times, occupying leading positions in the structure of morbidity and mortality worldwide. This article is dedicated to a comprehensive analysis of the problem of malignant neoplasms and the crucial role of early diagnosis in improving disease prognosis. The paper reviews the main epidemiological data, modern concepts of carcinogenesis, and details screening methods and early detection strategies for the most common cancer localizations. Special attention is paid to innovative technologies, including biomarkers, molecular genetic studies, and medical imaging methods. The importance of a multidisciplinary approach and increasing oncological alertness among primary care physicians is emphasized. The article will be useful for physicians of various specialties, medical university students, and researchers dealing with oncology problems.
References
1. Улмасов Т. Ш. Применение искусственного интеллекта в клинической микробиологии: новые горизонты диагностики // Лучшие интеллектуальные исследования. – 2026. – Т. 65. – №. 1. – С. 246-252.
2. UT S. Kh. RF Dry whey: a promising product for the food industry and agriculture //Web of Teachers: Inderscience Research. – 2025. – Т. 3. – №. 3. – С. 16-18.
3. Улмасов Т. Ш. Гайморит, Причины, Симптомы и Профилактика Лечения // TADQIQOTLAR jahon ilmiy-metodik jurnali. – 2025. – Т. 56. – №. 1. – С. 204-206.
4. Улмасов Т. Ш. Современные подходы к диагностике, профилактике и хирургическому лечению ишемической болезни сердца // "YURT FAXRI". – 2025. – Т. 1. – №. 1.
5. Ulmasov T. Sh. Prevention of Thyroid Diseases // 10. – 2024. – Т. 2. – №. 2. – С. 144-146.
6. Улмасов Т. Ш. О роли витаминов в жизненном цикле человека // Journal of Healthcare and Life-Science Research. – 2024. – Т. 3. – №. 1.
7. Tuttle, K. R., et al. (2023). Diabetic Kidney Disease: A Report From an ADA Consensus Conference. American Journal of Kidney Diseases, 81(5), 510–528.
8. Forbes, J. M., & Cooper, M. E. (2020). Mechanisms of Diabetic Complications priming the metabolic memory. Physiological Reviews, 100(1), 275–329.
9. Feldman, E. L., et al. (2019). Diabetic neuropathy. Nature Reviews Disease Primers, 5(1), Article 41.
10. Buse, J. B., et al. (2021). The metabolic and cardiovascular benefits of GLP-1 receptor agonists and SGLT2 inhibitors in type 2 diabetes. Diabetes Care, 44(6), 1290–1301.
11. Nauck, M. A., & Quast, D. R. (2023). Incretin-based therapies—glorious past, vibrant present, and gorgeous future. Molecular Metabolism, 69, 101683.
12. Battelino, T., et al. (2022). Continuous Glucose Monitoring and Metrics for Clinical Trials: An International Consensus Statement. Diabetes Care, 45(6), 1529–1537.
13. Brownlee, M. (2021). The Pathobiology of Diabetic Complications: A Unifying Mechanism. Diabetes, 54(6), 1615–1625.
14. Giacco, F., & Brownlee, M. (2019). Oxidative stress and diabetic complications. Circulation Research, 107(9), 1058–1070.
15. Saeedi, P., et al. (2020). Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas. Diabetes Research and Clinical Practice, 157, 107843.
