BOTULIZM KASALLIGIDA O‘TKIR NAFAS YETISHMOVCHILIGINING PATOGENEZI VA KLINIK XUSUSIYATLARI
Keywords:
Kalit so‘zlar: botulizm, botulotoksin, o‘tkir nafas yetishmovchiligi, diafragma, gipoksiya, giperkapniya, respirator falaj, intensiv terapiya.Abstract
Annotatsiya Botulizm — Clostridium botulinum tomonidan ishlab chiqariladigan botulotoksin ta’sirida yuzaga keluvchi og‘ir neyroparalitik kasallikdir. Kasallikning eng xavfli asoratlaridan biri o‘tkir nafas yetishmovchiligi bo‘lib, u nafas mushaklarining falajlanishi natijasida rivojlanadi. Ushbu maqolada botulizmda o‘tkir nafas yetishmovchiligining rivojlanish mexanizmlari, patogenezi, klinik kechishi, diagnostikasi va davolash tamoyillari tahlil qilingan. Botulotoksinning nerv-mushak sinapslariga ta’siri, diafragma va qovurg‘alararo mushaklar faoliyatining buzilishi hamda respirator asoratlarning rivojlanish bosqichlari yoritilgan.
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