CLINICAL-REPARATIVE EFFECTIVENESS OF LOCAL THERAPY BASED ON REPARATIVE AGENTS IN CHILDREN WITH RECURRENT HERPETIC STOMATITIS

Abstract

Recurrent herpetic stomatitis is one of the clinically significant viral diseases of the oral mucosa in childhood. The condition is most commonly associated with herpes simplex virus type 1 and is characterized by painful vesicular and erosive-ulcerative lesions, impaired food intake, sleep disturbance, salivation, local inflammatory reactions and a tendency to repeated exacerbations. In pediatric dental practice, standard treatment is mainly aimed at reducing viral activity, pain and secondary microbial contamination. However, the problem of accelerating epithelial repair of the oral mucosa and reducing the duration and frequency of relapses remains insufficiently resolved. The purpose of this article is to substantiate the clinical-reparative effectiveness of including reparative agents in local therapy for children with recurrent herpetic stomatitis. The proposed clinical model includes examination of children with recurrent herpetic lesions of the oral mucosa, assessment of lesion number and area, pain intensity, degree of hyperemia and edema, epithelialization time, recurrence frequency and patient quality-of-life indicators. Patients are planned to be compared according to two therapeutic approaches: standard local therapy and standard local therapy supplemented with reparative agents that support mucosal regeneration, hydration and epithelial barrier recovery. The expected clinical effect of the combined approach is faster epithelialization of erosive-ulcerative lesions, reduction of pain syndrome, improvement of oral intake, decrease in local inflammatory signs and longer remission. The integration of reparative components into pediatric dental treatment may improve the practical effectiveness of local therapy and contribute to a more individualized algorithm for managing recurrent herpetic stomatitis in children.